Mumakore achangopfuura, hyperbaric oxygen therapy (HBOT) yakabuda senzira yekudzivirira mukudzivirira uye kurapwa kwezvirwere zvemwoyo. The therapy inoshandisa musimboti wakakosha we "muviri weokisijeni kupihwa" kupa rubatsiro rwakakosha kumoyo nehuropi. Pazasi, isu tinonyura mune yakakosha mabhenefiti eHBOT, kunyanya mukugadzirisa nyaya dzine chekuita neiyo ischemic myocardial mamiriro.
Kusunungura Simba rePhysical Oxygen Supply
Tsvagiridzo inoratidza kuti mukati meiyo hyperbaric chamber pa2 atmospheres yekumanikidza (hyperbaric chamber 2 ata), kunyungudika kweokisijeni kunosvika kakapetwa kagumi kupfuura iyo pakumanikidzwa kwakajairika. Kunyudzwa uku kunoita kuti okisijeni ipinde munzvimbo dzakavharirwa kuyerera kweropa, pakupedzisira ichiendesa "okisijeni yekukurumidza" kune ischemic moyo kana uropi. Iyi nzira inoratidza kunyanya kubatsira kune vanhu vanotambura nechirwere che hypoxia nekuda kwemamiriro ezvinhu akadai secoronary artery stenosis uye cerebral arteriosclerosis, achipa kukurumidza kuzorora kubva kuzviratidzo senge chipfuva kusimba uye dzungu.
Kukurudzira Angiogenesisuye Kuvakazve Oxygen Channels
Hyperbaric oxygen therapy haingotauri zvinodiwa pakarepo asiwo inokurudzira kupora kwenguva refu nekukurudzira kusunungurwa kwevascular endothelial growth factor (VEGF). Iyi nzira inobatsira mukuumbwa kwekutenderera kutenderera munzvimbo dze ischemic, zvakanyanya kuvandudza kupihwa kweropa kumoyo nehuropi. Zvidzidzo zvakaratidza kuti mushure mezvikamu makumi maviri zveHBOT, varwere vecoronary artery disease vakaona kuwedzera kunoshamisa kwemyocardial microcirculation ne 30% kusvika 50%.
Anti-inflammatory uye Antioxidant Effects: Kudzivirira Sero Basa
Pamusoro pekugona kwayo kweokisijeni, HBOT inoshandisa anti-kuzvimba uye antioxidant mhedzisiro, zvichiita kuti ive yakakosha kuchengetedza moyo uye uropi kushanda kwesero. Tsvagiridzo inoratidza kuti kurapa kunogona kudzvanya nzira dzekuzvimba dzakadai seNF-κB, kuderedza kuburitswa kwezvinhu zvinokonzeresa seTNF-α uye IL-6. Uyezve, kukwidziridzwa kwesuperoxide dismutase (SOD) chiitiko kunobatsira kubvisa mahara radicals, kuderedza endothelial kukuvadzwa uye kupa mhedzisiro yekudzivirira kurwisa kusingaperi kuputika kwemamiriro senge atherosclerosis uye ane hukama neshuga shanduko yevascular.
Clinical Applications yeHyperbaric Oxygen muCardiovascular Diseases
Acute Ischemic Zviitiko
Myocardial Infarction: Kana ichishandiswa pamwe chete ne thrombolysis kana kupindira kwemishonga, HBOT inogona kunyatsoderedza myocardial cell apoptosis uye kuderedza dambudziko rekushaya arrhythmias.
Cerebral Infarction: Kutanga kushandiswa kwe hyperbaric oxygen therapy kunogona kurebesa kupona kwesero, kuderedza infarct size, uye kuwedzera basa retsinga.
Kugadziriswa Kwechirwere Chisingaperi
Stable Coronary Artery Disease: Varwere vanowanzoona zviratidzo zveangina zvakavandudzwa, kuwedzera kushivirira kwekurovedza muviri, uye kuderedza kuvimba nemishonga ye nitrate.
Rapid Atrial Arrhythmias (Slow Type): Kuburikidza nemigumisiro yakaipa inotropic, HBOT inobatsira kunonoka kwemwoyo, kuderedza myocardial oxygen kushandiswa, uye kugadzirisa ischemic mamiriro.
Chirwere cheHypertensive Heart: Chirwere ichi chinoderedza viscosity yeropa uye inoderedza left ventricular hypertrophy, zvinobudirira kunonoka kufambira mberi kwekukundikana kwemoyo.
Post-Stroke Sequelae: HBOT inobatsira mukugadziridza synaptic, inosimudzira mota basa uye kugona kwekuziva.
Kuchengetedza Profile yeHyperbaric Oxygen Therapy
HBOT inowanzoonekwa seyakachengeteka, ine mishoma mhedzisiro. Izvo zvinonyanya kunetsa zvinowanzova zvinyoro nyoro dzvinyiriro yezeve, iyo inogona kudzikiswa kuburikidza nekugadzirisa kudzvinyirira. Zvisinei, kupesana kwakasiyana kuripo, kusanganisira kubuda ropa, pneumothorax isina kurapwa, emphysema yakaoma, pulmonary bullae, uye heart block yakakwana.
Tarisiro Yeramangwana: Kubva Mukurapa Kuenda Kudziviriro
Tsvagiridzo ichiri kusimukira inoratidzira kugona kweHBOT mukunonotsa iyo atherosclerotic maitiro nekuvandudza vascular elasticity uye kudzikisa ropa lipid mazinga. Izvi zvinoisa hyperbaric oxygen seyero inoshanda yekurwisa "silent hypoxia," kunyanya muvanhu vane zviratidzo zvakaita sedzungu, kuderera kwendangariro, uye kushaya hope. Nekufambira mberi muAI-yakabatsirwa kurapwa optimization uye hunyanzvi hwekushandisa senge stem cell therapy, HBOT inogona kunge iri padanho rekuve musimboti wehutano hwehutano hwemoyo.
Mhedziso
Hyperbaric oxygen therapy inomira sechivimbiso, kwete-pharmacological solution yezvirwere zvemwoyo, yakavakwa panheyo ye "physical oxygen supply." Iyi nzira yakasiyana-siyana, kusanganisa kugadzirisa kwevascular, anti-inflammatory effects, uye antioxidant inobatsira, inoratidzira zvakakosha mune zvose zviri zviviri zvekukurumidzira uye kusingaperi kugadzirisa. Uyezve, kushandiswa kwe electrocardiograms (ECG) sechiratidzo chinotyisa che oxygenation uye ischemia inogona kushanda sehuchapupu hunokosha hwekliniki hunotsigira kushanda kweHBOT. Kusarudza HBOT hakusi kungosarudza marapirwo; zvinoreva kuzvipira kwakasimba pakubata hutano nekugara zvakanaka.
Nguva yekutumira: Kubvumbi-30-2025