Hyperbaric oxygen therapy inovandudza neurocognitive mabasa epashure-stroke varwere - retrospective analysis

Background:

Zvidzidzo zvakapfuura zvakaratidza kuti hyperbaric oxygen therapy (HBOT) inogona kuvandudza mashandiro emota uye ndangariro dzevarwere vepashure-stroke muchikamu chisingaperi.

Chinangwa:

Chinangwa chechidzidzo ichi ndechekuongorora mhedzisiro yeHBOT pamabasa ese ekuziva evarwere vepashure-stroke muchikamu chisingaperi.Chimiro, rudzi uye nzvimbo yesitiroko zvakaongororwa sezvinobvira zvinogadzirisa.

Nzira:

Ongororo yakadzokororwa yakaitwa kune varwere vakabatwa neHBOT yekusingaperi sitiroko (> 3 mwedzi) pakati pe2008-2018.Vatori vechikamu vakabatwa mune imwe nzvimbo yakawanda ye hyperbaric chamber ine mitemo inotevera: 40 kusvika ku60 zvidzidzo zvezuva nezuva, mazuva 5 pavhiki, musangano wega wega waisanganisira 90 min ye100% okisijeni pa2 ATA ne5 min air brakes yega yega 20 maminetsi.Clinically yakakosha kuvandudzwa (CSI) yakatsanangurwa se> 0.5 standard deviation (SD).

Mhinduro:

Chidzidzo chacho chaisanganisira varwere ve162 (75.3% varume) vane makore akaenzana e60.75 ± 12.91.Pakati pavo, 77 (47.53%) yakanga ine cortical sitiroko, 87 (53.7%) sitiroko yaive iri kuruboshwe hemisphere uye 121 yakatambura ischemic sitiroko (74.6%).
HBOT yakakonzera kuwedzera kukuru mune ese cognitive function domains (p <0.05), ine 86% yevanorohwa nesitiroko vachiwana CSI.Pakanga pasina misiyano yakakosha mushure meHBOT yecortical sitiroko zvichienzaniswa ne-sub-cortical sitiroko (p> 0.05).Hemorrhagic sitiroko yaive nekuvandudzwa kwakanyanya mukugadzirisa ruzivo nekukurumidza post-HBOT (p <0.05).Kuruboshwe hemisphere sitiroko yaive nekuwedzera kwepamusoro kwemota domain (p <0.05).Munzvimbo dzese dzekuziva, iyo yekutanga yekuziva basa yaive yakakosha kufanotaura kweCSI (p <0.05), nepo sitiroko yerudzi, nzvimbo uye rutivi zvaive zvisiri zvakakosha kufanotaura.

Mhedziso:

HBOT inokurudzira kuvandudzwa kwakakosha mumatunhu ese ekuziva kunyangwe mukupedzisira chisingaperi nhanho.Kusarudzwa kwevarwere vepashure-stroke yeHBOT kunofanira kubva pakuongorora kwekushanda uye nheyo dzepamusoro dzepfungwa dzepamusoro panzvimbo yerudzi rwekurohwa, nzvimbo kana rutivi rwechirwere.