Stroke, chirwere chinoparadza chinoratidzwa nekuderera kweropa rinoenda kuuropi kamwe kamwe nekuda kwechirwere chekubuda ropa kana ischemic pathology, ndicho chikonzero chechipiri chinotungamira murufu pasi rose uye chikonzero chechitatu chinotungamira mukuremara. Mhando mbiri huru dzestroke ischemic stroke (inosanganisira 68%) uye stroke yekubuda ropa (32%). Pasinei nekusiyana kwezvirwere zvavo muzvikamu zvekutanga, zvese izvi zvinoguma nekuderera kweropa uye cerebral ischemia inotevera panguva ye subacute uye chronic phases.
Kurohwa kweIschemic
Ischemic stroke (AIS) inoratidzwa nekuvharika kamwe kamwe kwetsinga yeropa, zvichikonzera kukuvara kwe ischemic kunzvimbo yakakanganiswa. Muchikamu cheacute, nzvimbo iyi yekutanga ine hypoxia inokonzera kuwanda kwe excitotoxicity, oxidative stress, uye activation ye microglia, zvichikonzera kufa kwakapararira kwetsinga dzeropa. Munguva yechikamu che subacute, kuburitswa kwe cytokines, chemokines, uye matrix metalloproteinases (MMPs) kunogona kubatsira mu neuroinflammation. Zvinonyanya kukosha kuti, mazinga akakwira eMMPs anowedzera kupenya kwe blood-brain barrier (BBB), zvichibvumira kufamba kwe leukocyte munzvimbo yakakanganiswa, zvichiwedzera kuzvimba.
Kurapa Kwazvino KweIschemic Stroke
Mishonga mikuru inoshanda yeAIS inosanganisira thrombolysis uye thrombectomy. Kuvhiyiwa kweropa netsinga kunogona kubatsira varwere mukati memaawa 4.5, uko kurapwa kwekutanga kunoratidza mabhenefiti makuru. Kana tichienzanisa ne thrombolysis, thrombectomy yemuchina ine mukana wakakura wekurapa. Pamusoro pezvo, mishonga isiri yemishonga, isingapindi muropa yakaita sekurapa neokisijeni, acupuncture, uye electric stimulation zviri kuwedzera kushandiswa senzira dzekurapa dzinoshandiswa pakurapa nenzira dzechinyakare.
Nheyo dzeHyperbaric Oxygen Therapy (HBOT)
Pakumanikidzwa kwegungwa (1 ATA = 101.3 kPa), mweya watinofema une okisijeni inosvika 21%. Mumamiriro ezvinhu emuviri, chikamu cheokisijeni yakanyungudika muplasma chishoma, chinongosvika 0.29 mL (0.3%) pa 100 mL yeropa. Mumamiriro ezvinhu ane hyperbaric, kufema okisijeni 100% kunowedzera huwandu hweokisijeni yakanyungudika muplasma zvakanyanya—kusvika pa3.26% pa 1.5 ATA uye 5.6% pa 2.5 ATA. Nokudaro, HBOT ine chinangwa chekuwedzera chikamu ichi cheokisijeni yakanyungudika, zvinobudirira.Kuwedzera kweokisijeni mumatishu munzvimbo dzine ischemic. Kana paine kumanikidzwa kwakanyanya, okisijeni inopararira zviri nyore mumatishu ane hypoxia, ichisvika kure kure nekupararira kwayo zvichienzaniswa nekumanikidzwa kwakajairika kwemhepo.
Kusvika pari zvino, HBOT yave kushandiswa zvakanyanya pakurapa sitiroko ye ischemic ne hemorrhagic. Zvidzidzo zvinoratidza kuti HBOT inopa mhedzisiro yekudzivirira tsinga kuburikidza nemaitiro akawanda akaomarara emamorekuru, biochemical, uye hemodynamic, anosanganisira:
1. Kuwedzera kwesimba reokisijeni mutsinga dzeropa, zvichivandudza kuendeswa kweokisijeni muuropi.
2. Kugadzikana kweBBB, kuderedza kuzvimba kweuropi.
3. Kuvandudza uropikufamba kweropa zvishoma nezvishoma, kunatsiridza kushandiswa kwesimba muuropi uye kugadzirwa kwesimba ukuwo zvichichengetedza homeostasis yemasero emaion.
4. Kudzora kuyerera kweropa muuropi kuderedza kumanikidzwa kwemuuropi uye kuderedza kuzvimba kweuropi.
5. Kuderedza kuzvimba kweuropi mushure mekurohwa.
6. Kuderedza apoptosis uye necrosismushure mekurohwa nestroke.
7. Kuderedza kushushikana kwe oxidative uye kudziviswa kwekukuvara kwe reperfusion, zvakakosha mu stroke pathophysiology.
8. Tsvagiridzo inoratidza kuti HBOT inogona kuderedza kupwanyika kweropa mushure mekubuda ropa kwemusana (SAH) kweaneurysmal.
9. Humbowo hunotsigirawo kubatsira kweHBOT mukusimudzira kuumbwa kwetsinga dzeropa uye angiogenesis.
Mhedziso
Kurapa neokisijeni ine hyperbaric kunopa nzira yakanaka yekurapa sitiroko. Sezvatinoramba tichiongorora matambudziko ekupora kwesitiroko, kuferefeta kwakawanda kuchave kwakakosha kuti tinzwisise nguva, chiyero, uye mashandiro eHBOT.
Muchidimbu, sezvatinoongorora mabhenefiti ekurapa neokisijeni yakakurisa pakurapa sitiroko, zvinova pachena kuti kushandisa mushonga uyu kune mukana wekuchinja nzira yatinobata nayo sitiroko ischemic, zvichipa tariro kune avo vanobatwa nechirwere ichi chinochinja hupenyu.
Kana uchida kutsvaga mushonga we hyperbaric oxygen therapy senzira inogona kushandiswa pakurapa sitiroko, tinokukoka kuti ushanyire webhusaiti yedu kuti udzidze zvakawanda nezvemakamuri edu epamusoro e hyperbaric oxygen. Nemhando dzakasiyana-siyana dzakagadzirirwa kushandiswa kumba uye nehunyanzvi, MACY-PAN inopa mhinduro dzinopa mushonga we oxygen wemhando yepamusoro uye wakanangana nerwendo rwako rwehutano nekudzoka.
Tsvaga zvigadzirwa zvedu uye kuti zvingavandudza sei hutano hwako pawww.hbotmacypan.com.
Nguva yekutumira: Kukadzi-18-2025