Bactericidal effect ye hyperbaric oxygen therapy mukukuvara kwekupisa

Nhanganyaya

Kukuvara kwekutsva kunowanzosangana muzviitiko zvekukurumidzira uye kazhinji inova chiteshi chekupinda chezvirwere. Zvinopfuura 450,000 kukuvara kwekutsva kunoitika gore negore zvichikonzera kufa kwe3,400 muUnited States. Kuwanda kwekukuvadzwa kwekutsva muIndonesia ndeye 0.7% muna 2013. Inopfuura hafu yeizvi Maererano nekuongorora kwakawanda pamusoro pekushandiswa kwevarwere vakabatwa nehutachiona hwehutachiona, humwe hwahwo hwakanga hunopesana nemamwe maantibioti. Kushandisahyperbaric oxygen therapy(HBOT) yekurapa kutsva ine zvakati wandei zvakanaka zvinosanganisira kugadzirisa hutachiona hwehutachiona, pamwe nekumhanyisa kupora kweronda. Nokudaro, chidzidzo ichi chine chinangwa chekuratidza kushanda kweHBOT mukudzivisa kukura kwebhakitiriya.

Nzira

Ichi chidzidzo chetsvakiridzo mutsuro uchishandisa dhizaini yeboka repashure-bvunzo. Tsuro makumi matatu nesere dzakapihwa kupiswa kwechipiri-dhigirii panzvimbo yemapfudzi nesimbi yesimbi ndiro yakambodziiswa 3 min. Mabhakitiriya tsika akatorwa pamazuva 5 uye 10 mushure mekusangana nekutsva. Iwo masampula akakamurwa kuita mapoka maviri, HBOT uye kutonga. Ongororo yenhamba yakaitwa pachishandiswa nzira yeMann-Whitney U.

Results

Gram-negative mabhakitiriya ndiwo ainyanya kuwanikwa pathogen mumapoka maviri. Citrobacter freundi ndiyo yainyanyozivikanwa mabhakitiriya eGram-negative (34%) anowanikwa mumhedzisiro yetsika dzemapoka maviri.

Kusiyana neboka rekutonga, pakanga pasina kukura kwebhakitiriya kunowanikwa mumigumisiro yetsika yeboka reHBOT, (0%) vs (58%). Kuderera kukuru kwekukura kwebhakitiriya kwakaonekwa muboka reHBOT (69%) kana ichienzaniswa neboka rinodzora (5%). Utachiona hwehutachiona hwakamira mu6 tsuro (31%) muboka reHBOT uye 7 tsuro (37%) muboka rekutonga. Pakazara, pakanga paine kukura kwakaderera kwebhakitiriya muboka rekurapa reHBOT kana ichienzaniswa neboka rekutonga (p <0.001).

Mhedziso

HBOT manejimendi inogona kuderedza zvakanyanya kukura kwebhakitiriya mukukuvadzwa kwekutsva.